Acetylsalicylic acid 75 mg, 30 tablets, Krka

Indications:
Acetylsalicylic acid Krka contains acetylsalicylic acid, which, when used in low doses, belongs to a group of medicines called antiplatelet agents. Platelets are small cells in the blood that cause blood to clot and are involved in thrombosis. When a blood clot forms in an artery, it stops the flow of blood and the oxygen supply is cut off. When this happens in the heart it can cause a heart attack or an episode of angina pectoris; in the brain it can cause a stroke.
Acetylsalicylic acid Krka is given to reduce the risk of blood clots forming, thus preventing the subsequent occurrence of:
- myocardial infarction
- cerebrovascular accidents
- cardiovascular problems in patients diagnosed with stable or unstable angina pectoris (a type of chest pain).
Acetylsalicylic acid Krka is also used to prevent blood clots from forming after certain types of heart surgery to widen or unblock blood vessels.
The decision regarding initiation of treatment and appropriate dosage should be made by the physician.
This medicine is not recommended in emergency cases. It can only be used as a preventive treatment.

Composition:
The active substance is acetylsalicylic acid.
Each gastro-resistant tablet contains 75 mg, 100 mg or 160 mg of acetylsalicylic acid.

Method of administration:
Adults:
Prevention of myocardial infarction:
- The recommended dose is 75 - 160 mg once a day.
Prevention of stroke:
- The recommended dose is 75 - 325 mg once a day.
Prevention of cardiovascular problems in patients diagnosed with stable or unstable angina pectoris (a type of chest pain):
- The recommended dose is 75-160 mg once a day.
Preventing blood clots after certain types of heart surgery:
- The recommended dose is 75-160 mg once a day.
This medicine should not be used in doses higher than recommended by your doctor, and the dose should not exceed 325 mg per day.
Elderly patients:
The recommended dose is the same as for younger patients. In general, acetylsalicylic acid should be used with caution in elderly patients who are prone to adverse reactions. Treatment should be reviewed at regular intervals.
Use in children and adolescents:
Acetylsalicylic acid should not be given to children and adolescents under 16 years of age unless specifically indicated by a doctor.

Precautions and contraindications:
Do not take Acetylsalicylic acid Krka:
- if you are allergic to acetylsalicylic acid or any of the other ingredients of this medicine (listed in section 6).
- if you are allergic to other salicylates or non-steroidal anti-inflammatory drugs (NSAIDs). NSAIDs are often used for arthritis or rheumatism and pain.
- if you have had an asthma attack or swelling of parts of your body such as your face, lips, throat or tongue (angioedema) after taking salicylates or NSAIDs.
- if you currently have or have ever had an ulcer in your stomach or small intestine or any type of bleeding, such as a stroke.
- if you have ever had problems with your blood not clotting properly.
- if you have severe liver or kidney problems.
- if you have severe heart problems, which may cause difficulty breathing or swelling of the ankles
- if you are in the last 3 months of pregnancy; you should not take doses higher than 100 mg per day.

Children and adolescents:
Acetylsalicylic acid can cause Reye's syndrome when given to children and adolescents. Reye's syndrome is a very rare disease that affects the brain and liver and can be life-threatening. For this reason, Acetylsalicylic acid Krka should not be given to children and adolescents under 16 years of age unless recommended by a doctor.

Pregnancy, lactation and fertility:
- if you are taking a medicine called methotrexate (for example, for cancer or rheumatoid arthritis) in doses higher than 15 mg per week.

Presentation:
30 gastro-resistant tablets

Warning:
Read all of this leaflet carefully before you start using this medicine because it contains important information for you. Always use this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you.