Beta Glucan Yestimun 1,3-1,6 ß-D 500 mg 100 capsules Aliness

Beta Glukan Yestimun 1,3-1,6 β-D 500 mg 100 capsules

Food supplement

Yestimun® Beta-Glucan is a completely natural and pure ingredient without additives. It consists exclusively of brewer's yeast (100% Saccharomyces cerevisiae).

The production process of Yestimun® Beta-Glucan complies with the following standards (certificates available on request):

• IFS
• BRC
• ISO 22000:2005
• bravo
• Kosher

Yestimun® Beta-Glucan is a completely natural and pure ingredient without additives. It consists exclusively of brewer's yeast (100% Saccharomyces cerevisiae).

Yestimun® Beta-Glucan is safe. It belongs to the food category because it is made from pure natural brewer's yeast. Safety has also been demonstrated in clinical trials on the effectiveness of Yestimun® Beta-Glucan. The ingredient can be consumed daily without negative side effects [Auinger et al. (2013), Eur J Nutr Vol 52, ed. 8, pp. 1913-1918].

Clinical studies have shown that the administration of Yestimun® does not cause side effects. All study participants rated the tolerability of the ingredient as “very good” or “good” [Auinger et al. (2013), Eur J Nutr Vol 52, Issue 8, pp. 19131918].

What are the functions of Yestimun® Beta-Glucan? How does training work?

The yeast cell itself is covered with a layer of manno-oligosaccharides (MOS). During the production process, this layer is carefully removed so that the intestinal immune cells can recognize the three-dimensional matrix of beta-glucans. The immune system is 70% dependent on the gut. The special structure of β-1,3-1,6-glucan is recognized by cells in the small intestine, just like the pathogen. There is a functional, rapid, nonspecific immune response that activates macrophages in Peyer's patches. Macrophages begin to destroy pathogens or activate other defense cells (B and T lymphocytes, dendritic cells). [Stier et al. (2014), Nutr J 13:38, p.2 ff. / Chan et al. (2009), J Hematol Oncol 2:25 / Volman et al. (2008), Physiol Behav 94:276-284].

No studies have yet been conducted to determine the appropriate dose. The purpose of the research we carried out was to obtain a health claim (approximately 2 x 450 mg/day).

[Graubaum et al. (2012), FNS 3, 738–746] Auinger et al. (2013), Eur J Nutr Vol 52, ed. 8, pp. 1913-1918]. [Rychlik et al. (2013), Acta Veterinaria Hungarica 61 (3), p. 297-308].

For children, the daily dose may be lower than for adults. We have not performed a clinical study on children, but scientific analysis shows that 7 mg/kg body weight provides reliable results.

Yestimun® can be taken at any time of the day. A good solution is to take the preparation regularly at the same time - this way you can avoid missing a dose. Clinical trial participants took one capsule (450 mg) twice a day, for example with breakfast and dinner [Graubaum et al. (2012), FNS 3, 738–746 / Auinger et al. (2013), Eur J Nutr Vol 52, ed. 8, pp. 1913-1918].

There are various theories regarding this issue. It is sometimes recommended to take beta-glucans some time before eating, so that the structure of the molecule is better recognized as it passes through the digestive tract without interference from other molecules. Our clinical studies have shown that the effects also occur when the preparation is taken during meals - not necessarily between or after meals. The preparation will be effective as an ingredient of dietary supplements and functional foods. [Graubaum et al. (2012), FNS 3, 738–746 / Auinger et al. (2013), Eur J Nutr Vol 52, ed. 8, pp. 1913-1918].

Yestimun® Beta-Glucan is dispersible, but not soluble. Due to this fact, it can be added to liquid preparations such as drinks or syrups, drinks, shakes

The purity of our beta-glucan is at least 85%. The production process includes various washing steps to obtain a pure beta-glucan structure and to remove other components such as mannan-oligosaccharides, fats and proteins.

Yestimun® Beta-Glucan is a preparation suitable for vegans and vegetarians. It consists exclusively of brewer's yeast (100% Saccharomyces cerevisiae).

We analyzed the vitamins contained in yeast from our local brewers as it is a rich source of natural vitamins. Yestimun® Beta-Glucan is produced from brewer's yeast in a separation process that consists of at least three steps: autolysis, then separation, first wash in slightly alkaline conditions at boiling point, then separation, second wash in neutral conditions at the boiling point and then separation. During these processes, all soluble substances (sugars, proteins, fats) are washed away, so we can assume that due to the long boiling time, most vitamins are washed out or deactivated.

Yestimun® Beta-Glucan is produced from brewer's yeast. Yeast proteins can cause allergic reactions. During the production process, almost all proteins are removed, leaving only pure beta-glucan. Although beta-glucans come from brewer's yeast (Saccharomyces cerevisiae), they are a pure isolate and do not contain enough yeast protein to cause an allergic reaction.

Yestimun® Beta-Glucan was tested for gluten content and no trace of it was found. This is due to a combination of enzymatic and alkaline hydrolysis and several washing steps during the production process

Brewer's yeast is grown on wort derived from barley. For brewer's yeast, levels of 200 ppm and above are typically used. Gluten is a protein complex based on several amino acids. During enzymatic autolysis (the first stage), most of the gluten is hydrolyzed and the individual amino acids do not cause an allergic reaction. The cell wall is then subjected to a caustic treatment. Proteins, fats and mannan-oligosaccharides are hydrolysed and washed. The final step is rinsing, which finally removes the remaining fat, mannose and amino acids. Yestimun® Beta-Glucan becomes a highly purified glucan.

We have our own gluten analysis equipment, set to max. 20ppm gluten. All analysis results showed that Yestimun® Beta-Glucan does not contain gluten.

Unfortunately, there are no official health claims for Yestimun® Beta-Glucan yet. Although all clinical results were positive, EFSA (European Food Agency) invalidated the ability to officially communicate the properties of beta glucans. However, it has been proven in clinical studies that Yestimun® Beta-Glucan has a positive effect on the immune system. [Graubaum et al. (2012), FNS 3, 738–746 / Auinger et al. (2013), Eur J Nutr Vol 52, Issue 8, pp. 1913-1918].

Yestimun® Beta-Glucan has been tested at different pH values ​​and temperatures. The results showed that there were no changes in the structure of the ingredient. It is also stable in an acidic environment and can be added, for example, to acidic drinks.

Beta-glucan is able to survive in stomach acid. Our research has shown that Yestimun® Beta-Glucan is truly acid resistant. Therefore, the entire molecule can pass through the stomach and reach the intestine, where it is recognized by receptor cells [Rahar et al. (2011), J Adv Pharm Technol Res, Apr-Jun; 2(2): 94-103].

Yestimun® Beta-Glucan should be stored in a closed container in a cool, dry place away from light. Once the box is opened, it must be closed hermetically and carefully so that the product maintains its quality.

Yeast and oat beta-glucan belong to the fiber group, but they have a different structure and a completely different function. Oat beta-glucan has a β-1,3-1,4 linkage type, while yeast beta-glucan - 1,3-1,6-β-D-glucan. The following numbers show the different types of connections.

Chemical structure of oat beta-glucan (1,3-1,4 bonds)

In breweries, brewer's yeast grows on natural malt grains. These grains contain all the vitamins and trace elements necessary for yeast growth. Unlike baker's yeast, no additional units are required. Brewer's yeast requires a long maturation period in which it absorbs and accumulates additional minerals and vitamins from the grain. These unique characteristics have made brewer's yeast a popular and effective dietary supplement.

Ingredients: Yestimun® (Brewer's yeast extract (Saccharomyces cervisiae) 85% beta 1,3-1,6 β-D glucan, capsule shell: (binding agent: hydroxypropyl methylcellulose).

Recommended daily dose : 1-2 capsules per day before meals. Do not exceed the recommended daily dose.

Package contents: 100 capsules

Precautions: Do not exceed the recommended daily dose. The product cannot be used by pregnant women, nursing women and children without medical consultation. The product cannot be used as a substitute for a varied diet. Do not use if you are allergic to any of the ingredients. We recommend a balanced diet and a healthy lifestyle. Protect from light, store at room temperature, in a dry place, out of the reach of small children.

Manufacturer: Medicaline Ostrówiec 15005-480 Karczew