ACTION AND MECHANISM

- [LAXATIVE]. An osmotic laxative that increases the osmotic pressure inside the small intestine, causing the release of water into the intestinal lumen, inducing a rapid bowel movement, generally within four hours. - [ANTACID]. Sodium bicarbonate neutralizes excess gastric acid.

SENIORS

No specific problems have been described, but in these patients, kidney or heart failure is more common.

CONTRAINDICATIONS

- Hypersensitivity to any component of the medication.- [DIARRHEA].- [INTESTINAL OBSTRUCTION].- [APPENDICITIS] or [INTESTINAL PERFORATION].

DOPING

This medication may produce a positive result in a doping test. Its use is prohibited both in and out of competition.

PREGNANCY

Its effectiveness and safety have not been evaluated, therefore its use is not recommended.

INDICATIONS

Symptomatic treatment of: - [CONSTIPATION].- [GASTRIC HYPERACIDITY].- [DYSPEPSIA].

LACTATION

It is unknown whether this medication is excreted in breast milk, and the possible effects on the infant. It is recommended to discontinue breastfeeding while using this medication.

CHILDREN

Its safety and effectiveness have not been evaluated, therefore its use is not recommended.

GUIDELINES FOR PROPER ADMINISTRATION

The preparation should be dissolved in half a glass of water. The preparation can be taken before or after meals.

POSOLOGY

DOSAGE: - Adults, oral: 1-2 teaspoons/24 h, although the dose can be increased if necessary. Laxative: 1-2 teaspoons at bedtime and the same dose the next day on an empty stomach, allowing, if possible, a few minutes of rest.

PRECAUTIONS

- [RENAL INSUFFICIENCY]: In cases of renal insufficiency, sodium accumulation can occur, leading to hypernatremia and increased fluid retention. Due to its magnesium content, there is a risk of hypermagnesemia. - [HEART INSUFFICIENCY]: Sodium can cause hypernatremia, leading to alterations in the Na+-K+ ATPase pump and decreasing the effectiveness of cardiac contraction. In addition, water retention can lead to hypervolemia, which increases preload and further impairs heart function. [HIGH BLOOD PRESSURE]: The sodium content of this medication may increase fluid retention and blood pressure. [METABOLIC ALKALOSIS]: Sodium bicarbonate is a systemic antacid that is absorbed in the gastrointestinal tract; therefore, prolonged use may result in metabolic alkalosis. In sodium-restricted diets, it should be noted that each dose contains 606.5 mg of sodium.

ADVERSE REACTIONS

The adverse reactions to this medicine are mild and infrequent: - Digestive. Tartaric acid may cause diarrhea. - Electrolyte imbalances. Very rarely, after a chronic overdose or in patients with renal insufficiency, hypermagnesemia may occur. - Rarely (<1%): due to sodium absorption, risk of edema and hypertension; large doses may produce metabolic alkalosis (more frequent if there is renal insufficiency).

COMPOSITION

MAGNESIUM CITRATE: 110 MILLIGRAMS
MAGNESIUM SULFATE: 40 MILLIGRAMS
SODIUM BICARBONATE: 400 MILLIGRAMS
TARTARIC,ACID: 370 MILLIGRAMS
MANNITOL: 50 MILLIGRAMS